Hyaluronidase

Hyaluronidase Source: mammalian testes EC: 3.2.1.35 Apperence:A white or yellow-white powder Pharmaceutical grade DESCRIPTION Hyaluronidase is a glycoprotein containing 5% mannose and 2.7% glucosamine. Optimum pH range is 4.5-6.0. The enzyme catalyzes the hydrolysis of endo-N-acetylhexosaminic bonds of hyaluronic acid and chondroitin sulfate A and C (but not B), primarily to tetrasaccharide residues. TheHyaluronidase is extracted from bovine testes, and has been chromatographically purified to remove trace contaminating proteases. SpecificationItemSpecificationMethodAppearanceA white or yellow-white powderIdentificationCompliesEPAppearance of solutionClearEPpH4.5 - 7.5EPLoss on dryingLess than 5.0%EPBacterial endotoxinsLess than 0.2 IU per IU of hyaluronidaseEPLimit of tyrosineLess than 0.25 µg per USP Hyaluronidase U.USPActivityMore than 300 IU/mg powderEP